Prof. Fredrik Bäckhed, PhD
Sahlgrenska University Hospital
SE-413 45 Göteborg
University of Gothenburg is the largest university in Scandinavia. The
Sahlgrenska Academy at the University of Gothenburg has a long-standing focus
and a strong international reputation in metabolic and cardiovascular
Team leader Dr. Fredrik Bäckhed aims to identify novel therapeutic and
diagnostic targets for the metabolic syndrome by focusing on the role of the
gut microbiota, using a highly interdisciplinary research approach to unravel
how the gut microbial community affects lipid metabolism and inflammation. The
team currently consist of 8 members and maintains a gnotobiotic facility at
UGOT. The group which was started in mid 2006 is an interdisciplinary team
with core competencies in biochemistry, molecular biology, functional
genomics, physiology, and gnotobiology.
Key people in the team
Dr. Fredrik Bäckhed, Associate Professor in molecular medicine
Gunnel Östergren-Lundén, lab manager
Carina Arvidsson, heads the gnotobiotic facility
Dr. Christopher Reigstad, role of lipids and glycolipids in metabolic
Jenny Felin, bile acid metabolism and function
Rahil Hezaveh, lipid metabolism
Bäckhed F, Ding H, Wang T, Hooper LV., Koh GY, Nagy A, Semenkovich CF, Gordon
JI, The gut microbiota as an environmental factor that regulates fat storage.
Proc Natl Acad Sci USA 101, 15718-15723 (2004).
Bäckhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Host-bacterial
mutualism in the human intestine. Science 307, 1915-1920 (2005).
Ley RE, Bäckhed F, Turnbaugh P, Lozupone C, Knight R, Gordon JI. Obesity
alters gut microbial ecology. Proc Natl Acad Sci USA 102, 11070-11075 (2005).
Bäckhed F, Manchester JK, Semenkovich CF, Gordon JI, Mechanisms underlying the
resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci USA
104, 979-984 (2007).