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VTT Expression Service - From gene to protein

VTT Expression Service can help researchers and companies in production of recombinant proteins. VTT has more than 30 years of experience in protein production technology research in different hosts systems such as;

  • the bacterium Escherichia coli
  • the yeasts Saccharomyces cerevisiae, Pichia pastoris and Kluyveromyces lactis
  • the filamentous fungus Trichoderma reesei
  • baculovirus/insect cells
  • plants and plant cell cultures

This knowledge of many expression hosts enables the best case-specific choice for each protein. The expression vector and host strain are selected from our versatile collection, and purification tags can be added to expression constructs when required. We have the facilities and know-how to cultivate these production hosts in bioreactors up to pilot scale (1.2 m2), and expertise on downstream processing and protein purification.

The Expression Service offers a customer-oriented solution to help researchers and companies to successfully produce their recombinant proteins. We can provide the customer with complete tailor-made service for producing a protein of interest, even including cloning of the target gene. Alternatively, we can help the customer with any individual step along this route from gene isolation to purification and analysis of the final product.